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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c9521c07ca51231abe370030794b9ce31a24e1414133fef7e38163ec05d9fe' 
  AND token = 'deBPtbwkNpm1z1LcSklzyEamwViVa1QJeqZWtUF6NEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}