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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d6968f328594c1bd9f1a3da3d82f4158052439dd8647b02aa43a64d6b3c901' 
  AND token = 'UimhfLAGY3A043YCU13kTmS50gISabjl9ob4HlTZm6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}