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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1489d3e8b6bba87169f9addadbf0976670b5d23500def08e47db307da77f45f5' 
  AND token = 'KoHdvCRXe6iH8kI42FKK7/nsQU/iqU9wFUz3/4h4TI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}