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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd34606b8aa52a3f38bb3a88f46f23342e4773989dc6135c33e4312e584b689f5' 
  AND token = 'O+1fFwuXvKjPTO4qW0Qdcii2WFF3FMmKqIfZ8SSvIMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}