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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42678f05e0d4057513079596f81b59d03bc36ea3cd0c91ab19ecb57893ea0c32' 
  AND token = 'gvFJi21iYkv2ILjaDqCt34np/T59qOwfku3B+1t3NhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}