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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f514f18e9de46ece653ab29c207ca2750b8c17074e5a98960f9f4f6425025e8' 
  AND token = 'PO1QPWQU/0Za5NxCpM+BO3WguwrYpIoTdWETV/QJsbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}