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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c37e94fedb8b795d10b7c96096af63b9e3fea89a559e113a24aeff399c7e360' 
  AND token = 'xXtIQja8ycYdBu3TKAiEhWjeA9L1caRl5XBL/FB6VRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}