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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9bb2123e3c8eefb510828f4d4981a3e5abf9ed4ed442efff14965d200635bb' 
  AND token = '2qizn9u523mJ8SKrdMdak+EWhU8Ncz7JQKSpj4UXf9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}