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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9fabe204b2de3b6eb6cd7d50ec33976194da2f8005ccde8a932330f098973b' 
  AND token = 'sdmbrdUnwoWzyRcoqATUJM5kq0xYWc6S+CFFHCX/8Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}