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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bca19c2b9ec81fe69ed96e439a65fd697e027f45faf8740b095cfa3fd483449' 
  AND token = 'GEXCdqgKCtMaYIixxIr92nM6xx9KpNVhDf0nj1T+igk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}