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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60231bedcc3023cf383aaf5dfea137e32af64ac1affff7e4f80e29c72fe02a33' 
  AND token = 'jEqVihcMuNNFtw5d/4D/2/dBrUizqb3wUTkVwmJ7Ic8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}