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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa4e116cee502bc678806e4ab4809b40fb5d1f21ee036f47856690ee2f1dbdf' 
  AND token = 'Uimpc2qpQJiEbOE438yyuihnwxb9x9YaLlx6Cqqp5xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}