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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc24986ce476d04bd85cc6d9c7778422f1f194c8f92529de5ff65fba29b7521' 
  AND token = 'Aw6ynheoZ2R61Ai2fBGobBE/qTcn2A8cyhvuL2Ngq2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}