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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cccd575803642677dc67843dbd09df5ff611dae3fdb20e671e6dd1e96c445d3' 
  AND token = '0L0Mj278Hhb7cpll6HKJMWWWfil1T1ZFgCf0PuC07J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}