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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1916943b59937741a4de7ae6d0e8589680f2e961c2dcf84ed03e73230f33ce1c' 
  AND token = 'MatIYPjMo5AQ2XCnMIfaTRt1OlmtKcgIyecvs97nlaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}