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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1f022cc767650e32215cc777f4bc87386690420e57f54ea9058c90f95d6cb1' 
  AND token = 'vz9MUh04lc9T+K7NVJcAtyOtTSw23dat6JaBBZLxL2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}