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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b33208a63abbabbe25128cc1c7fbad40e65fda591c56c8e6e7635fa74ce181' 
  AND token = 'KjocJW8rf9/cFzutDq+8Qo0pWpj6Cqjs4Ts/jeuMsgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}