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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fc05ab89edb2421bf773f32f03e999c57d9b8eb9e168fb749d06dc33869ce6' 
  AND token = 'nUFuraOdr1anpf7Mj/TKSeCfEGg7p8ZvVyI8veFibZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}