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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764694b1b14dbf8ad3da706f8049465e60207dcb25f1618a3cf1cdfbe30dfe46' 
  AND token = '6/Wr2119+OQUi0erT3wiFbA2JrQ61uaZNZwxcXxtp6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}