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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58ec227401708a272831193cd8be636ad65e01c1a1bf23e8f522bb0de2be0e2' 
  AND token = 'NL7R0ovY5zc9gNBKM05PA33VIQwRS0c1bD1bj9tVP3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}