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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144ec1f3893b5835820060656227a14cf318e88904eccde1b2478260114fb3fb' 
  AND token = '/FOE7CHdtJoacRaQINVE10jAoJ5Ys+t+PDQvYyv5doY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}