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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ee1b66490c275f6dc5fa75a016b239a2dab25e9e2d4111644f3def50e0d74a2' 
  AND token = 'LGyBedwSM/X9RRtez9YFxjaRAeQPjAG+9zM4KtcBb28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}