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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11c111e80b034706eae4afab5dc7506960022080068afa59efacf95d58fd99d' 
  AND token = 'ZbZHglml14gXu6xfebdd7RildlGL7Z4zSgFsSnqjxP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}