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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299dd93683388ea4df1bc42abb453a467e81306bfb6aeb5539926ae12172308e' 
  AND token = 'Yf8zzK7fzF0f+EMjWVidVC4b8auR/38E6NtiqYimzeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}