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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86791cd10e9e7c551f85f548d1b7a1a2317935704da7aca1f05b7ad1bd7ee275' 
  AND token = 'uaIcchjwPmVz5S4VEmqUPIPpIiNLDZ+I34JOGq3Ygu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}