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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac1168e1c0534822488b4c79c357000fb86353a3c2a0c10a148694d5a649708' 
  AND token = '442Bgl7ktUTmX0SwI4Jldd8/UFViF+1FStF8u+IaGLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}