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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd670f78d32f97f7e227a1c5b0251962b440fb5f0a8189aaeaabcee23b9ceb110' 
  AND token = 'ppIEfYKSl6PiqOt9NNYUf6/+/R2BSkLQSg/5vrctLGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}