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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99cf2f2b4a41cc85ca9cdfd51a1e0db7eb54561b1d99736821a47fb545294b30' 
  AND token = 'NXEw4xgTcLI/F3fsqgJWSNTN4dANWaCpURNnK6d7uHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}