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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '299e02005450d66548e8e5bc53874b98ebef3ca0bb3da98e4124880d2cf3783c' 
  AND token = 'ml7PJfhe8/Xmi67kcLAHpxdAGIFq/TmhV20xMNGCJE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}