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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14cec51cf6d6e49b38087e519cb0235b36b67d9210edd6fe80a7b1d698a2bdfa' 
  AND token = 'Vs9HSNL7eyDwuZbAWnARAoZgY3C52AUvejIJQ4PQGdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}