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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6a6c8a32bf021e9a8266ceca15d5a46ed722fd75d35faf66a88989843e9dc2b' 
  AND token = 'PaVuzEUR6nTPTa51X6YEk6yAPWtiz/8J2DqjaFY4tDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}