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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428ae571254cdaa4f673db267817b322ad32d572d7c2eeeae5ac53a3b1ef56c5' 
  AND token = 'KrM+kuoCGzmIOKdSHmfHTr+4xIimwrt3wSj8CAjgvKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}