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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a464e8e7c2f70b111ae8f27cceedb4d3424eb7252fe4172adbcf44fe0feda7' 
  AND token = 'E8Ozj0NxS3gSjaZ1Md0lZwu72I2HH4s6ftVAUuTP0aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}