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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480c0ef521a5a00054c98d0a9760892323801c52e7c7235e890491755f142bc5' 
  AND token = '6SYkTg/d4PQU1S+j1gPeotGnmyx6k0RbRsjI6ZLxcRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}