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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14e59798824bc337b1aa6384bc69053dabccf5857d3287d9df60fde563a00e8b' 
  AND token = 'mk6KDxBdEMcdYrW10NxOADMg8ClqTY7pIXZKYRrISj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}