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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f4ae175e5614c83bd92beb9a28f7be7be14f05e3599bbe30551eee467692ec' 
  AND token = 'zx+lY8vutVuVM+a/LDUKrQ0KweQk43KYhHPPq3XXpkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}