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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0652b6bf00879f0815a6e75ccff2426f88d5ab3a6cd9a68ca89da86b9716c209' 
  AND token = 'GECPfau6QtPubvnD7V8iVD1MWTxj1wR5h0tObp4WJ5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}