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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '239a6f933efdbe782d6648ca2c011b4219d6f1c4c3c3e0a6e49092d18870f3a7' 
  AND token = 'xq5ZkUU9peJ+inIlSpmRSmsXjHXc9rzpjpr3U5pu9a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}