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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e485e58e80348e83aadf7643aef34dc75ae6c3710768a20eb053644775cd57b' 
  AND token = '53jK8WGG4YD52dbHVkmlHNoQ12TLNVgj9G5H4Z7xc28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}