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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '875b6f80ee2a75b266b67511a822a61e80659b452bb6f65614d00ca2210cc99d' 
  AND token = 'pS/AQw1qeMlmOFR/P78+XY0H8ihH0DHSaqrd3/3k2io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}