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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '112a08668f23ae46e2634ea8f2ea8b1c639e8f6bab403c4064b39aad142f08d6' 
  AND token = 'RTWL1cnBV1W7D7uFsEuyJ4rlD8LzyTmUvJUD2A6EfpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}