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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e94317f2f54140e00ac08049f6b4c138265c6be7d5c9bbe1ceb7eff17cdcf31f' 
  AND token = 'IHZmGTita7+BpnjEaPSUn23nxjGEB02FSFlP3qs6qEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}