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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0115052ef77d29de1d25d11ff247368573874de18c87e67ff0b559ac7cbd3ee5' 
  AND token = 'WgZq+UOxYBpeWgitipv9FP38CeLM3RbB4KU9ye2PtTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}