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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4826f405f27726020c028b8cf6ea9890489d3b24ae4a4d2ebc5a2f068876ad4' 
  AND token = 'kIypzwf/f9zr0Nat8G0HOestMZVKk42HsKQaFDOfQeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}