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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b104f81c53240b2ca9a41ee21f7850530280b27623c4f18773f3795b4e2457c0' 
  AND token = '1epf1ReC03uLc1hFWH4kNNrbyKxMEqTg/nr61pi+yso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}