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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18543f91f8067e308b3bbdc39788f67ddb7d7face0883d139ef383fb828f080' 
  AND token = 'oxD0JVYNmgcX2p+Az9o+f7HJFMW9INgcBr3cyrvkMT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}