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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52587bcc247b12cc4123c55eac10cdb95a3f745c05752dd184b2c95c9e9cb443' 
  AND token = 'ZNqyxgkrYv1ZvB901ZRNDE4QoL/6q7pQLyBX8kZMT6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}