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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312d330048bc4092fd1ea1e6b0e9303c0aeb6194e9c3646ee4bc78687d86c6f8' 
  AND token = 'LrMFCxXGMTOn7UGkN7ywjHhpvNRDYD58PICGD/hJkYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}