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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1f311a671dd17abc012a906b0924b48d2f8e178f06fd2f60ded99434611c188' 
  AND token = 'CVFv9MFF83u9w+UuxcSAj/+gCY58PQ/SXy4DK3nR3bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}