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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b325cfa19cb396c9be2b8aa9b29830b9a4e03580625153e8bfad2d9a211136f8' 
  AND token = 'Pw+nrmSg+Tabxc5QlkYL9X6vDFz8uEpaENoSw4M36Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}